Professor Mikhail Blagosklonny is one of the greatest things ever to happen to the world of science. With certainly a calling for research in the field of oncology and aging, professor Mikhail has committed much of his research time mulling the best approaches to the management, prevention, and treatment of cancer. the scholar with a keen focus on the age old question of aging has also sought to make us understand the secrets of aging while proposing ways of its possible conquest.
Mikhail Blagosklonny enrolled in the Pavlov State Medical University in St. Petersburg after high school. While in this university, he earned an M.D. in internal medicine and proceeded to complete a Ph.D. in cardiology and experimental medicine. Following his graduation with a Ph.D., Mikhail got hired by the New York Medical college Valhalla to the position of an associate professor. He then moved to the Ordway Research Institute where he became the senior scientist and stayed in the position until 2009. From Ordway Research Institute, Mikhail joined the Roswell Park Cancer Institute becoming a professor of oncology.
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Professor Mikhail currently works at the Rosewell Park Cancer Institute in New York USA. His research interests fall within the fields of cellular and molecular biology, clinical research on tumor suppressors and oncogenes, apoptosis and signal transduction, the cell cycle and cancer drugs, aging and aging diseases.
Professor Mikhail has written more than 3000 articles, book chapters, and reviews.his is the editor in chief and founder of the cell cycle. Co-editor and the co-founder of the aging, oncoscience, and oncotarget. He has also served as the associate editor for cancer research, an international journal of cancer, cell death, and differentiation, cancer biology and therapy, the American journal of pathology and autophay.
Professor Mikhail TOR signaling hypothesis. TOR is a nutrient sensing protein kinase that regulates growth and metabolism in eukaryotes. This kinase is the target for inhibition by the drug rapamycin pioneered by Mikhail for anti-aging.
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As one of the most incurable and therefore deadliest diseases that ever affected humans, cancer serves as a longstanding challenge for all the people in the medical and research fields. Thus, it is no wonder that a scientist as brilliant as Mikhail Blagosklonny joined in the wagon not too long ago and came up with theories on how to stop aging as well as cancer.
The doctor and professor attended the First Pavlov State Medical University of St. Peterburg, a well-known institution in Russia with no less than 100 years of history. Mikhail Blagosklonny spent a good portion of his life in this place, for he received a Medicinae Doctor degree with a specialty in internal medicine there, and then continued to obtain a Ph.D. in cardiology and experimental medicine.
Read more: Answering the ultimate question “What is the Proximal Cause of Aging?”
Some time after his graduation, in 2002, Blagosklonny uprooted himself from the Soviet and moved to the United States, particularly in New York, to become an associate profession in New York Medical College situated within the hamlet of Valhalla in the same state. His stay in this academy, however, was short-lived as Mikhail Blagosklonny transferred to the Ordway Research Institute in Albany to take on the senior scientist post. He served this facility until 2009 before he accepted a position at the Roswell Park Research Insitute as a professor of oncology.
Mikhail Blagosklonny focuses his intellect and experimental skills at present in looking for treatments for cancer and aging that can offer long-term effectivity. His main concern is to find a cure that is capable of exterminating the infected cancer cells in the human body without killing the healthier cells along the process. Also, he wishes to understand how the current anti-aging medications function so as to turn up with a more efficient solution to the issue of getting old. See: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249451/
During the researches he conducted, he was able to hypothesize that the signaling of a particular enzyme within the system with the help of rapamycin, a widely acclaimed drug for cancer, can potentially allow the users to prolong their lives and prevent aging. How this works is that the mechanistic target of rapamycin will connect to various protein chains inside the body to create two unique protein complexes. These new chains can now imitate the behavior of another kinase called threonine or serine which has the role of managing cell proliferation, growth, survival, motility, and many others.
Read works by Mikhail Blagosklonny on Google Scholar